The short paper published by ONTOX explains the principles of probabilistic risk assessment, including how and when New Approach Methodologies (NAMs) are meant to be used.
Probabilistic risk assessment is a quantitative approach to estimating the likelihood and magnitude of adverse health effects in a population due to exposure to hazardous substances. Probabilistic risk assessment considers variability and uncertainty in exposure and toxicity data, generating probability distributions of potential health outcomes. It is used to make risk management decisions and prioritise resources for preventing and controlling exposure to hazardous substances.
ONTOX project aims for probabilistic risk assessment, an approach that ONTOX advocates when discussing how to facilitate a paradigm shift from hazard to risk assessment with a future full implementation of NAMs.
However, ONTOX realises the need to explain the term “probabilistic risk assessment” from an ONTOX perspective when discussing this topic whit relevant stakeholders and internally in ONTOX. Therefore, ONTOX developed this two-pager to explain the term and give examples of probabilistic risk assessment.
