Find here all scientific publications related to the ONTOX project

Published in 2022

Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi

Caloni F., De Angelis I., Hartung T.

Archives of Toxicology | May 2022

Mitochondria as the Target of Hepatotoxicity and Drug-Induced Liver Injury: Molecular Mechanisms and Detection Methods

Mihajlovic M., Vinken M.

International Journal of Molecular Sciences | Vol. 23, March 2022

Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation

Koch K., Bartmann K., Hartmann J., Kapr J., Klose J., Kuchovská E., Pahl M., Schlüppmann K., Zühr E., Fritsche E.

Frontiers in Toxicology | Vol. 4, March 2022

Probabilistic risk assessment – the keystone for the future of toxicology

Maertens A., Golden E., Luechtefeld T. H., Hoffmann S., Tsaioun K., Hartung T.

ALTEX – Alternatives to animal experimentation | Vol. 39, January 2022

Published in 2021

Unsupervised Representation Learning for Proteo-chemometric Modeling

Kim P. T., Winter R., Clevert D.-A.

International Journal of Molecular Sciences | Vol. 22, December 2021

Img2Mol – accurate SMILES recognition from molecular graphical depictions

Clevert D.-A., Le T., Winter R., Montanari F.

Chemical Science | Vol. 42, November 2021

Connexin-Based Channel Activity Is Not Specifically Altered by Hepatocarcinogenic Chemicals

Leroy K., Pieters A., Cooreman A., Van Campenhout R., Cogliati B., Vinken M.

International Journal of Molecular Sciences | Vol. 22, October 2021

Primary Human Hepatocyte Spheroids as Tools to Study the Hepatotoxic Potential of Non-Pharmaceutical Chemicals

Vilas-Boas V., Gijbels E., Leroy K., Pieters A., Baze A., Parmentier C., Vinken M.

International Journal of Molecular Sciences | Vol. 22, October 2021

A systematic review of in vitro models of drug-induced kidney injury

Irvine A. R., van Berlo D., Shekhani R., Masereeuw R.

Current Opinion in Toxicology | Vol 27, September 2021

Safer chemicals using less animals: kick-off of the European ONTOX project

Vinken M., Benfenati E., Busquet F., Castell J., Clevert D. A., de Kok T. M., Dirven H., Fritsche E., Geris L., Gozalbes R., Hartung T., Jennen D., Jover R., Kandarova H., Kramer N., Krul C.,
Luechtefeld T., Masereeuw R., Roggen E., Schaller S., Vanhaecke T., Yang Ch., Piersma A. H.

Toxicology | Vol. 458, June 2021

In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic Approach

Tabernilla A., dos Santos Rodrigues B., Pieters A., Caufriez A., Leroy K., Van Campenhout R., Cooreman A., Gomes A. R., Arnesdotter E., Gijbels E., Vinken M.

International Journal of Molecular Sciences | Vol. 22, May 2021