Bernard Staumont is a project manager and postdoctoral researcher at the Biomechanics Research Unit at the University of Liège, one of the partners of the ONTOX project. Bernard is motivated to work at ONTOX because of the opportunity to work in an interdisciplinary environment, learn from and collaborate with many domain experts and work together to develop new approach methodologies that will reduce the use of animal testing. At ONTOX, Bernard focuses on creating physiological and ontology maps – sophisticated in silico tools that visually represent biological processes. These maps are instrumental in unraveling complex biological interactions, laying the groundwork for predictive toxicology and enhancing next-generation risk assessment strategies. Bernard’s work embodies the ONTOX mission to advance sustainable, human-relevant toxicological research.
Find out more about Bernard and dive into the following lines of the next ONTOX #YoungScientist Series.
Bernard, what was behind your motivation to become a scientist?
It’s hard to pinpoint exactly, but during primary and high school, I had a strong affinity for mathematics – perhaps influenced by my father, who was a math teacher. Over time, my interest in science grew, particularly in chemistry and biology, as I enjoyed learning about the mechanisms at work in both the human body and the environment.
What is your major motivation to be a part of the ONTOX project?
My main motivation to be a part of ONTOX is the opportunity to work in an interdisciplinary environment, learn from and collaborate with many domain experts and work together to develop new approach methodologies that will reduce the use of animal testing.
As part of the ONTOX project, what are your responsibilities?
I co-supervise the research work conducted by our team at ULiège within ONTOX WP1 and WP5, focusing on the development of physiological and ontology maps. These in silico tools aim to visually map biological processes, much like Google Maps, but for proteins and genes. They enable us to illustrate the biology of specific functions in the body and integrate data provided by other project partners, such as information on chemicals or adverse effects. This approach enhances our understanding of disease mechanisms and supports the development of new strategies for chemical risk assessment. Additionally, I am actively involved in project management tasks, including reporting, drafting deliverables, and coordinating activities related to these objectives.
Can you describe your primary scientific expertise?
I completed my Master’s in Bioengineering with a focus on chemistry and bio-industries, covering topics from analytical chemistry to agri-food technologies. However, I chose to pursue both my Master’s and PhD theses in the field of cancer research, primarily using molecular and cell biology techniques, along with some in vivo models. During my PhD, I focused on developing new therapeutic approaches for malignant pleural mesothelioma (cancer of the pleura), targeting DNA repair mechanisms and a specific growth factor, TGF-alpha.
Why did you become a Postdoctoral Researcher at the Biomechanics Research Unit (University of Liège)?
Before my current position, I worked first as a researcher during my PhD and then as a full-time project manager in my first job post-PhD. Then, I had the opportunity to join the Biomechanics Research Unit, where I can combine both research and project management. This role allows me to focus on coordination, writing, and reviewing, while also developing new research skills, especially in the in silico field, which I had not previously explored.
Who is your biggest inspiration in science or general?
My family has always been supportive and a constant source of inspiration, both in my work and beyond. Their dedication to their jobs, while balancing family life and personal hobbies, has truly inspired me. In science, I truly admire Professor Arsène Burny. He was one of the initiators of the Télévie, a charitable campaign in Belgium which raises funds every year for scientific cancer research. He is also a truly kind person and a great scientist to discuss with.
What are your expectations from ONTOX? What has this work already given you?
ONTOX provided me with the opportunity to enter the toxicology community and learn through collaboration with numerous partners. More than that, it allowed me to grow as a scientist and connect with both skilled researchers and great individuals.
Do you work on other interesting scientific projects that aim to reduce or replace testing in animals?
Yes, I am involved in other projects focusing mostly on the development of in silico/computer models addressing different issues such as knee defects or cardiovascular diseases (e.g., In Silico World and SimCardioTest projects). I am also a member of the Virtual Physiological Human Institute which aims to promote the adoption and use of in silico technologies in research and clinic. In silico methods offer a huge potential for reducing, refining, and replacing animal testing.
Have you achieved something in your career of which you are particularly proud?
Presenting my PhD thesis in front of my family and several friends was a truly rewarding experience. It was a special moment, to receive their support. I also feel a sense of pride whenever a colleague I have helped – especially with writing and reviewing – earns a grant or an award.
What do you think is the greatest challenge in your life as a young scientist?
I believe one of the greatest challenges today is practising effective and humble communication of our research to prevent the spread of misinformation and to help restore public trust in science.
Can you share your future scientific plans?
I am very happy with my current position, as it offers great flexibility for both my research and non-research activities. I am also keen to continue working in the field of toxicology in the years to come. That said, I remain open to exploring new opportunities and taking on new challenges when the time feels right. Whatever path I choose, I will likely stay closely connected to science and innovation.
Besides making the world better with science, do you have other hobbies?
I have been playing saxophone and clarinet since childhood, and I really enjoy our Friday band rehearsals, along with the few concerts we perform each year. We actually discussed forming a band with the ONTOX musicians 😊. I also love travelling and exploring both urban and natural landscapes around the world.
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